منابع مشابه
Treatment of germ cell tumors--update 2006.
Testicular cancer is considered a malignancy with a high cure rate even in patients with metastatic disease. Treatment strategies are based on the extent of the disease and prognostic factors and require cooperation of medical specialists such as medical oncologists, radiation oncologists and urologic surgeons. Today, cure rates of 95–99% for patients with early stage testicular cancer and 50–9...
متن کاملBiology and Molecular Markers of Malignant Gonadal Germ Cell Tumors
5 Original Publications 8 Abbreviations 9 Introduction 10 Review of the Literature 11 1. Germ cells 11 1.1 Inner cell mass and embryonic stem cells 11 1.2 Factors essential for maintenance of pluripotency and self-renewal 11 1.3 Development and migration of germ cells 14 2. Gonadal development 16 2.1 Ovarian differ entiation 17 2.2 Testicular differentiation 18 3. GATA transcription factors in ...
متن کاملClinical characteristics of malignant ovarian germ cell tumors
This study was aimed to investigate the clinical characteristics, treatment and prognosis effect of malignant ovarian germ cell tumors (MOGCTs). A total of 39 patients with MOGCTs treated at Gynecology Obstetrics in Tianjin Central Hospital were enrolled from January 1999 to November 2009 in this study. All the patients underwent pathological examination and diagnosis was confirmed. We used uni...
متن کاملThe Epidemiology of Malignant Germ Cell Tumors: The EUROCARE Study
Germ cell tumors (GCTs) comprise a heterogeneous group of tumors in terms of histology, age at diagnosis, anatomical site and prognosis. Here we describe the epidemiology of GCT on the basis of data from European population-based cancer registries (CRs) analysed in the framework of the EUROCARE (European Cancer Registrybased study on survival and care of cancer patients) project, which has moni...
متن کاملPediatric malignant germ cell tumors show characteristic transcriptome profiles.
Malignant germ cell tumors (GCT) of childhood are rare and heterogeneous neoplasms thought to arise from primordial germ cells. They vary substantially in their natural history and show important clinical differences from their adult counterparts. To address the biological basis for these observations, we have undertaken a comprehensive analysis of global gene expression patterns in pediatric m...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 1990
ISSN: 0923-7534
DOI: 10.1093/oxfordjournals.annonc.a057721